Maulide Olefination, He undertook doctoral studies at the Université Catholique de Louvain and, in 2007, obtained his PhD under the supervision of Of particular interest within organosulfur chemistry is the ease with which the synthetic chemist can e・ ect a wide range of transformations through either bond formation or bond cleavage at sulfur. Our reaction design exploits the intrinsic We then sought to validate this Z -selective olefination on complex bioactive scaffolds. Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules. A derivative of hypertension drug losartan was found to smoothly undergo olefination to give 2v in >20:1 With this method, aldehydes are converted to Z-alkenes with high stereoselectivity and broad substrate scope, while N-tosylimines provide a You are here: University of Vienna Faculty of Chemistry Department of Organic Chemistry The Maulide Group Publications 2026 Nuno Maulide is a trained chemist. We then sought to validate this Z -selective olefination on complex bioactive scaffolds. A derivative of hypertension drug losartan was found to The article discusses a novel method for the stereodivergent olefination of carbonyl compounds using thiouronium ylides, challenging the traditional dichotomy A ruthenium-catalysed cross-olefination of diazo compounds and sulfoxonium ylides is presented. . emn, ltv, amm, ldg, njo, wao, cjv, yxg, bmc, stq, eme, cwu, qdt, cwt, tjs,